Successful multiple organ donation after donor brain death due to Actinomyces israelii meningitis

TitleSuccessful multiple organ donation after donor brain death due to Actinomyces israelii meningitis
Publication TypeJournal Article
Year of Publication2017
AuthorsLagunes L, Len O, Sandiumenge A, Martínez-Saez E, Pumarola T, Bodro M, Macías A, Silva JT, Nuvials FX, Charco R, Moreso F, Pont T
Volume19
Issue4
Date PublishedAug
KeywordsActinomyces israelli, Meningitis, multiple organ donation
Abstract

The increasing gap between availability of solid organs for transplantation and the demand has led to the inclusion of donor organs that, according to current guidelines, may be discarded, some of them because of the possibility for transmission of infection to the recipients. We present the first report, to the best of our knowledge, of a case of a brain-dead donor with a localized and treated Actinomyces israelii central nervous system infection who, after a thorough evaluation, provided organs for successful transplant procedures in four recipients. There was no evidence of transmission of infection within a 6-month follow-up. Relative contraindications must be individualized in order to expand the number of real organ donors, emphasizing caution in rare causes for brain death in which patients should be thoroughly evaluated for possible donation.

DOI10.1111/tid.12711
Alternate JournalTranspl Infect Dis
Notify Library Reference ID4648

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