Kidney damage during organ recovery in donation after circulatory death donors: data from UK National Transplant Database.

TitleKidney damage during organ recovery in donation after circulatory death donors: data from UK National Transplant Database.
Publication TypeJournal Article
Year of Publication2012
AuthorsAusania F, White SA, Pocock P, Manas DM
JournalAmerican journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons// Am J Transplant
Volume12
Issue4
Pagination932 - 6
Date Published2012
ISBN Number1600-6143
Other Numbers100968638
Keywords*Death, Sudden, Cardiac, *Kidney/in [Injuries], *Organ Preservation, *Tissue and Organ Procurement, *Tissue Donors/sd [Supply & Distribution], Adolescent, Adult, Brain Death, Cadaver, Child, Child, Preschool, Delayed Graft Function, Female, Graft Survival, Great Britain, Humans, Infant, Infant, Newborn, Kidney Transplantation, Male, Middle Aged, Retrospective Studies, Survival Rate, Treatment Outcome, Young Adult
Abstract

During the last 10 years, kidneys recovered/transplanted from donors after circulatory death (DCD) have significantly increased. To optimize their use, there has been an urgent need to minimize both warm and cold ischemia, which often necessitates more rapid removal. To compare the rates of kidney injury during procurement from DCD and donors after brain death (DBD) organ donors. A total of 13 260 kidney procurements were performed in the United Kingdom over a 10-year period (2000-2010). Injuries occurred in 903 procedures (7.1%). Twelve thousand three hundred seventy-two (93.3%) kidneys were recovered from DBD donors and 888 (6.7%) from DCD donors. The rates of kidney injury were significantly higher when recovered from DCD donors (11.4% vs. 6.8%, p

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