Neonatal transfusion-transmitted hepatitis C virus infection following a pre-seroconversion window-phase donation in Sweden.

TitleNeonatal transfusion-transmitted hepatitis C virus infection following a pre-seroconversion window-phase donation in Sweden.
Publication TypeJournal Article
Year of Publication2013
AuthorsWaldenstrom J, Konar J, Ekermo B, Norder H, Lagging M
JournalScandinavian journal of infectious diseases// Scand J Infect Dis
Volume45
Issue10
Pagination796 - 9
Date Published2013//
ISBN Number1651-1980
Other Numbersucx, 0215333
Keywords*Blood Transfusion/ae [Adverse Effects], *Hepatitis C/di [Diagnosis], *Hepatitis C/tm [Transmission], Hepatitis C Antigens/bl [Blood], Humans, Infant, Newborn, Male, Plasma/vi [Virology], RNA, Viral/bl [Blood], Sweden, Viral Core Proteins/bl [Blood]
Abstract

A 9-day-old child developed a transfusion-transmitted hepatitis C virus (HCV) infection following a pre-seroconversion window-phase donation. Retrospective analysis of donor plasma revealed detectable HCV core antigen (154 fmol/l), as well as HCV RNA (87,000 IU/ml). Of 5.24 million Swedish plasma samples from December 1998 to September 2012, 5 additional window-phase donations were identified.

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