Reverse vertical transmission of hepatitis-B from transfusion-infected children to biological mothers.

TitleReverse vertical transmission of hepatitis-B from transfusion-infected children to biological mothers.
Publication TypeJournal Article
Year of Publication2014
AuthorsKhanna R, Gupta E, Alam S
JournalIndian pediatrics// Indian Pediatr
Volume51
Issue9
Pagination739 - 41
Date Published2014//
ISBN Number0974-7559
Other Numbersgm2, 2985062r
Keywords*Blood Transfusion/ae [Adverse Effects], *Hepatitis B/tm [Transmission], *Infectious Disease Transmission, Vertical, Humans, Infant, Infant, Newborn, Male
Abstract

BACKGROUND: Perinatal and horizontal are the common modes of transmission of hepatitis-B virus in children., CASE CHARACTERISTICS: Two mother-child pairs with children having received multiple blood transfusions in past., OBSERVATION: Both the mothers developed acute hepatitis-B infection whereas children were demonstrated to be having chronic infection with hepatitis-B., OUTCOME: One mother cleared her hepatitis-B infection whereas it persisted in the other. Both children required anti-viral treatment., MESSAGE: Hepatitis-B virus may rarely get transmitted from infected children to their mothers causing acute infection.
Notify Library Reference ID4528