Malaysian child infected with Plasmodium vivax via blood transfusion: a case report.

TitleMalaysian child infected with Plasmodium vivax via blood transfusion: a case report.
Publication TypeJournal Article
Year of Publication2013
AuthorsAnthony CN, Lau Y-, Sum J-, Fong M-, Ariffin H, Zaw W-, Jeyajothi I, Mahmud R
JournalMalaria journal// // Malar J
Volume12
Pagination308
Date Published2013//
ISBN Number1475-2875
Other Numbers101139802
Keywords*Blood Transfusion/ae [Adverse Effects], *Malaria, Vivax/di [Diagnosis], *Plasmodium vivax/ip [Isolation & Purification], Child, DNA, Protozoan/ge [Genetics], Humans, Malaria, Vivax/pa [Pathology], Malaysia, Male, Neoplasms, Germ Cell and Embryonal/co [Complications], Neoplasms, Germ Cell and Embryonal/th [Therapy], Plasmodium vivax/ge [Genetics], Polymerase Chain Reaction, Sequence Analysis, DNA
Abstract

Malaria may be a serious complication of blood transfusion due to the asymptomatic persistence of parasites in some donors. This case report highlights the transfusion-transmitted malaria of Plasmodium vivax in a child diagnosed with germ cell tumour. This child had received blood transfusion from three donors and a week later started developing malaria like symptoms. Nested PCR and sequencing confirmed that one of the three donors was infected with P. vivax and this was transmitted to the 12-year-old child. To the best of the authors' knowledge, this is the first reported transfusion-transmitted malaria case in Malaysia.

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