Upper-extremity deep venous thrombosis complicating whole-blood donation.

TitleUpper-extremity deep venous thrombosis complicating whole-blood donation.
Publication TypeJournal Article
Year of Publication2004
AuthorsCovin RB, Rich NL, Aysola A
Pagination586 - 90
Date Published2004
ISBN Number0041-1132
Other Numberswdn, 0417360
Keywords*Blood Donors, *Upper Extremity/bs [Blood Supply], *Venous Thrombosis/et [Etiology], Adult, Contraceptives, Oral, Sequential/ae [Adverse Effects], Enoxaparin/tu [Therapeutic Use], Female, Humans, Risk Factors, Thrombophilia/di [Diagnosis]

BACKGROUND: Up to 36 percent of blood donors may experience a donation-related complication. Fatigue, bruises, hematomas, and vasovagal reactions comprise the great majority of donor reactions and injuries. Serious complications are rare., CASE REPORT: A 20-year-old female taking the third-generation oral contraceptive desogestrel/ethinyl estradiol and ethinyl estradiol (Mircette) developed bruising and increased pain and swelling of her right arm over a 5-day period after whole-blood donation. She was a first-time donor and the venipuncture was reported as being mildly traumatic. There was no personal or family history of thrombosis., RESULTS: Ultrasound examination of her upper extremity revealed the presence of a deep venous thrombosis that required treatment with enoxaparin sodium for 5 days and warfarin for 6 months. Evaluation for thrombophilia was negative. The only risk factor for thrombosis was use of oral contraceptives., CONCLUSION: Although serious complications from whole-blood donation are rare, they may occur. Deep venous thrombosis should be considered in a donor presenting with increasing pain and swelling after blood donation.

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