Anti-M causing delayed hemolytic transfusion reaction.

TitleAnti-M causing delayed hemolytic transfusion reaction.
Publication TypeJournal Article
Year of Publication1983
AuthorsAlperin JB, Riglin H, Branch DR, Gallagher MT, Petz LD
Pagination322 - 4
Date Published1983
ISBN Number0041-1132
Other Numberswdn, 0417360
Keywords*Blood Transfusion/ae [Adverse Effects], *Hemolysis, *MNSs Blood-Group System, Chromium Radioisotopes/du [Diagnostic Use], Coombs Test, Erythrocytes, Female, Humans, Middle Aged

A 52-year-old gravida 1, para 1 woman with M- red cells experienced a delayed hemolytic transfusion reaction and exhibited an anti-M antibody following the infusion of four units of M+ red cells. Measurements of erythrocyte survival using 51Cr-labeled donor M+ and M- red cells and in vitro studies of monocyte-macrophage phagocytosis of sensitized reagent red cells implicate anti-M in the pathogenesis of hemolysis.

Notify Library Reference ID4393

Related Incidents