| Title | Encephalopathy, stroke, and myocardial infarction with DMSO use in stem cell transplantation |
| Publication Type | Journal Article |
| Year of Publication | 2007 |
| Authors | Chen-Plotkin AS, Vossel KA, Samuels MA, Chen MH |
| Journal | Neurology |
| Volume | 68 |
| Issue | 11 |
| Pagination | 859 - 61 |
| Date Published | 41334 |
| Type of Article | Case Reports |
| ISSN | 1526-632X (Electronic) 0028-3878 (Linking) |
| Accession Number | 17353475 |
| Keywords | Brain Injuries / chemically induced / diagnosis / *etiology, Dimethyl Sulfoxide / *adverse effects, Female, Humans, Male, Middle Aged, Myocardial Infarction / chemically induced / diagnosis / *etiology, Stem Cell Transplantation / *adverse effects, Stroke / chemically induced / diagnosis / *etiology |
| Abstract | Stem cell transplants are established therapy for hematologic and solid tumor malignancies. Known neurological complications of stem cell transplantation include CNS infection, seizures, strokes, metabolic encephalopathy, and hemorrhage. We report two cases of autologous stem cell transplantation complicated by cerebral infarction and myocardial injury. We postulate that the cryopreservative dimethyl sulfoxide may be responsible. |
| DOI | 10.1212/01.wnl.0000256716.04218.5b |
| Alternate Journal | Neurology |
| Notify Library Reference ID | 330 |
Encephalopathy, stroke, and myocardial infarction with DMSO use in stem cell transplantation
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