|Title||Fatal thrombotic thrombocytopenic purpura as a rare complication following allogeneic stem cell transplantation.|
|Publication Type||Journal Article|
|Year of Publication||2000|
|Authors||Chemnitz J, Fuchs M, Blau W, Hartmann P, Wickenhauser C, Scheid C, Schulz A, V D, Söhngen D|
|Pagination||527 - 9|
|Keywords||Fatal Outcome, Female, Hematopoietic Stem Cell Transplantation, Humans, Middle Aged, Plasma Exchange, Purpura, Thrombotic Thrombocytopenic, Transplantation, Homologous|
Thrombotic thrombocytopenic purpura (TTP) is a rare disease which, together with hemolytic uremic syndrome, is subsumed under thrombotic microangiopathy. After stem cell transplantation (SCT), this syndrome represents a possibly fatal complication with a higher incidence in allogeneic SCT than in autologous SCT. Although plasmapheresis offers an encouraging treatment modality in classic TTP, this seems less effective in bone marrow transplant-associated microangiopathy. This is probably due to a different etiology. We present a case of transplant-associated TTP with a fatal outcome despite multiple courses of plasmapheresis.
|Notify Library Reference ID||325|