Successful liver, kidney, and pancreas transplantation from a donor with cerebral emboli from a left atrial myxoma

TitleSuccessful liver, kidney, and pancreas transplantation from a donor with cerebral emboli from a left atrial myxoma
Publication TypeJournal Article
Year of Publication2005
AuthorsCanter RJ, Abt PL, Litzky LA, Frank A, Abt AB, Sellers MT, Markmann JF, Olthoff KM, Naji A, Shaked A
JournalTransplantation Proceedings
Volume37
Issue10
Pagination4334 - 6
Date PublishedDec
Type of ArticleCase Reports
ISSN0041-1345 (Print) 0041-1345 (Linking)
Accession Number16387113
Keywords*Hepatectomy, *Intracranial Embolism, *Kidney Transplantation, *Liver Transplantation, *Myxoma / pathology, *Nephrectomy, *Pancreas Transplantation, *Pancreatectomy, Adolescent, Heart Atria / pathology, Humans, Male, Tissue and Organ Harvesting / *methods, Tissue Donors / *statistics & numerical data
Abstract

Although transmission and engraftment of donor-derived malignancies is rare in recipients of solid organ transplants, it is associated with unfavorable allograft and patient survival. Therefore, a recent history of malignancy is considered a contraindication to organ donation. Although atrial myxomas are benign cardiac tumors of stromal origin, they can lead to systemic embolization with ectopic myxoma formation. We report successful liver, kidney, and pancreas transplantation into 3 recipients from a donor with cerebral emboli from a left atrial myxoma. Eighteen months after transplantation, all 3 patients enjoy good allograft function and are free of donor-derived atrial myxoma. Although the duration of follow-up in this report is limited, we suggest that the presence of atrial myxoma should not be viewed as an absolute contraindication to organ recovery, particularly in view of the shortage of organ donors and the attendant morbidity and mortality for patients on waiting lists.

DOI10.1016/j.transproceed.2005.10.028
Alternate JournalTransplant Proc
Notify Library Reference ID294

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