| Title | Acquired haemophilia due to factor VIII inhibitors in ovarian hyperstimulation syndrome: case report. |
| Publication Type | Journal Article |
| Year of Publication | 2003 |
| Authors | Nakauchi-Tanaka T, Sohda S, Someya K, Kono K, Hamada H, Yoshikawa H |
| Volume | 18 |
| Issue | 3 |
| Pagination | 6 |
| Date Published | Mar |
| ISSN | 0268-1161 |
| Accession Number | 12615815 |
| Keywords | Adult, Blood Coagulation Factors / tu [Therapeutic Use], Delivery, Obstetric, Factor VIII / ai [Antagonists & Inhibitors], Female, Hemophilia A / dt [Drug Therapy], Hemophilia A / et [Etiology], Humans, IM, Infant, Newborn, Male, Ovarian Hyperstimulation Syndrome / co [Complications], Ovarian Hyperstimulation Syndrome / me [Metabolism], Pregnancy |
| Abstract | A 31-year-old nulligravida woman developed an acquired factor VIII inhibitor associated with severe ovarian hyperstimulation syndrome (OHSS). She developed haematouria, ecchymosis, and intramuscular bleeding following the severe OHSS. Laboratory examinations showed a markedly prolonged activated partial thromboplastin time and a low level of factor VIII activity. Treatment with prothrombin complex concentrate and factor VIII inhibitor bypassing agent was successful in reducing the inhibitor so that she delivered a healthy baby via spontaneous vaginal delivery. Acquired haemophilia is a life-threatening disorder. This is the first case report of acquired haemophilia in OHSS. |
| URL | http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med4&AN=12615815 |
| Alternate Journal | Hum.Reprod. |
| Notify Library Reference ID | 1760 |
Acquired haemophilia due to factor VIII inhibitors in ovarian hyperstimulation syndrome: case report.
Related Incidents
- 482 - Acquired hemophilia - Oocyte