Donor-to-host transmission of Candida glabrata to both recipients of corneal transplants from the same donor

TitleDonor-to-host transmission of Candida glabrata to both recipients of corneal transplants from the same donor
Publication TypeJournal Article
Year of Publication2009
AuthorsTappeiner C, Goldblum D, Zimmerli S, Fux C, Frueh BE
JournalCornea
Volume28
Issue2
Pagination228 - 30
Date PublishedFeb
ISSN1536-4798 (Electronic) 0277-3740 (Linking)
Accession Number19158573
Keywords*Candida glabrata, *Tissue Donors, Aged, Candidiasis / pathology / *transmission, Corneal Transplantation / *adverse effects, Eye Infections, Fungal / pathology / *transmission, Female, Humans, Microscopy, Electron, Middle Aged
Abstract

PURPOSE: To report 2 cases of exogenous Candida glabrata endophthalmitis after penetrating keratoplasty in recipients of corneas from the same donor transplanted on the same day. METHODS: Case reports with ophthalmologic, electron microscopic, and microbiological findings including fungal strain analysis. RESULTS: Two patients developed fungal keratitis and endophthalmitis caused by the same C. glabrata strain within 1 day after penetrating keratoplasty of corneas from the same donor on the same day. Donor-to-host transmission was postulated when eye bank sterility checks were repeatedly negative. CONCLUSIONS: A short death-to-harvesting time, routine donor rim cultures, and respecting of a time interval before transplantation may provide an additional safety feature in dealing with corneal tissue from high-risk donors.

URLinternal-pdf://Tappeiner - Donor_to_Host_Transmission_of_Cglabrata-1369678336/Tappeiner - Donor_to_Host_Transmission_of_Cglabrata.pdf
DOI10.1097/ICO.0b013e318183a3e3 00003226-200902000-00023 [pii]
Notify Library Reference ID1524

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