Chagas seropositive donors in kidney transplantation

TitleChagas seropositive donors in kidney transplantation
Publication TypeJournal Article
Year of Publication2004
AuthorsSousa AA, Lobo MC, Barbosa RA, Bello V
JournalTransplantation Proceedings
Pagination868 - 9
Date PublishedMay
ISSN0041-1345 (Print) 0041-1345 (Linking)
Accession Number15194296
Keywords*Tissue Donors, Chagas Disease / prevention & control / *transmission, Female, Follow-Up Studies, Humans, Kidney, Kidney Transplantation / *physiology, Male, Nitroimidazoles / *therapeutic use, Time Factors, Trypanocidal Agents / *therapeutic use

Among 239 kidney transplantations between September 1992 and September 1997, nine recipients' kidneys were obtained from Chagas seropositive donors. All of these patients were treated with benznidazole (5 mg/kg/d) for 14 days starting on day 0. None of them experienced acute Chagas disease or seroconversion even after 10 years follow-up. We concluded that, due to cadaver shortage, donors with positive serology for Chagas disease should not be excluded.

Alternate JournalTransplant Proc
Notify Library Reference ID1427

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