Title | Epstein-Barr virus lymphoproliferative disease of donor origin after kidney transplantation: a case report |
Publication Type | Journal Article |
Year of Publication | 1995 |
Authors | Renoult E, Aymard B, Gregoire MJ, Bellou A, Hubert J, Hestin D, Audouin J, Lederlin P, Kessler M |
Journal | Am J Kidney Dis |
Volume | 26 |
Issue | 1 |
Pagination | 84 - 7 |
Date Published | Jul |
ISSN | 0272-6386 (Print) 0272-6386 (Linking) |
Accession Number | 7611274 |
Keywords | *Herpesvirus 4, Human / genetics, *Tissue Donors, Aged, B-Lymphocytes, Chromosome Inversion, Chromosomes, Human, Pair 1, DNA Transposable Elements / genetics, DNA, Viral / genetics, Female, Herpesviridae Infections / genetics / *transmission / virology, Humans, Kidney Transplantation / *adverse effects, Lymphoproliferative Disorders / *etiology / genetics / virology, Transforming Growth Factor beta / genetics, Tumor Virus Infections / genetics / *transmission / virology |
Abstract | A case of an Epstein-Barr virus (EBV)-associated B lymphoproliferative disorder presented as a renal transplant obstruction is reported. The diagnosis was made from histology, immunohistochemistry, and EBV expression studies. Cytogenetic analysis showed the tumor to be of donor origin and revealed chromosomal translocation 46, XY, inv (1)(p35; q41), involving the EBV insertion site 1(1p35) and transforming growth factor beta 2(1q41) loci. |
DOI | |
Notify Library Reference ID | 1311 |