Immune hemolysis after an ABO mismatched renal transplant

TitleImmune hemolysis after an ABO mismatched renal transplant
Publication TypeJournal Article
Year of Publication1989
AuthorsPerkins AC, Richards VL, Gibson J, Joshua DE, Johnson JR, Kronenberg H
JournalAust N Z J Med
Pagination345 - 6
Date PublishedAug
ISSN0004-8291 (Print) 0004-8291 (Linking)
Accession Number2675813
Keywords*Kidney Transplantation, ABO Blood-Group System / *immunology, Adult, Anemia, Hemolytic, Autoimmune / *etiology / immunology, Autoantibodies / analysis, Cyclosporins / adverse effects / immunology, Graft Survival / drug effects, Humans, Male

We describe a case of immune hemolysis due to anti-B occurring in a blood group B patient 16 days after a cadaveric renal transplantation from a blood group O donor. Transfusional support was initially required and the direct antiglobulin test (DAT) remained positive for 80 days. Cyclosporin A (CSA), which was used for rejection prophylaxis in this case, has unique immunosuppressive capabilities which protects transplanted organs from rejection, but which might permit this type of 'graft versus host' reaction.

Notify Library Reference ID1265

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