Title | Donor transmission of malignant melanoma in a lung transplant recipient 32 years after curative resection |
Publication Type | Journal Article |
Year of Publication | 2010 |
Authors | Bajaj NS, Watt C, Hadjiliadis D, Gillespie C, Haas AR, Pochettino A, Mendez J, Sterman DH, Schuchter LM, Christie JD, Lee JC, Ahya VN |
Journal | Transpl Int |
Volume | 23 |
Issue | 7 |
Pagination | e26 - 31 |
Date Published | Jul |
ISSN | 1432-2277 (Electronic) 0934-0874 (Linking) |
Accession Number | 20444242 |
Keywords | Donor Selection, Fatal Outcome, Female, Humans, Lung Neoplasms / *etiology, Lung Transplantation / *adverse effects, Male, Melanoma / *etiology, Middle Aged, Pulmonary Fibrosis / *surgery, Skin Neoplasms, Tissue Donors |
Abstract | In the current era of organ shortages and long wait times for life-saving transplants, marginal or extended donors are increasingly being considered; one such category of marginal organs is from donors with a previous history of malignancy. Melanoma in particular has been associated with increased risk of developing late recurrence. In this report, we describe a case of fatal donor melanoma transmission to a 64-year-old lung transplant recipient 32 years after surgical excision of the melanoma. Based on this report and review of the available literature, we conclude that a history of donor melanoma, regardless of the stage and time interval from 'curative' surgical resection, should remain a strong relative contraindication to transplantation. |
DOI | 10.1111/j.1432-2277.2010.01090.x |
Notify Library Reference ID | 123 |