Status:
Ready to upload
Record number:
1664
Adverse Occurrence type:
MPHO Type:
Estimated frequency:
75 of 906 patients (8%) undergoing allogeneic HCT developed idiopathic pneumonia syndrome.
Time to detection:
23 days (median)
Alerting signals, symptoms, evidence of occurrence:
Retrospective cohort study criteria for idiopathic pneumonia syndrome: clinical, radiographic, microbiology, and pathology data.
Demonstration of imputability or root cause:
Correlation of platelet transfusions from apheresis collections or pooled platelet rich plasma collections. No difference in IPS occurrence, HR= 1.36 for both.
Imputability grade:
1 Possible
Groups audience:
Keywords:
Reference attachment:
Suggest references:
Vande Vusse, L.K., Madtes, D.K., Bolgiano, D. and Watkins, T.R. (2015). The association between platelet transfusion and idiopathic pneumonia syndrome is unaffected by platelet product type. Transfusion, 2015, doi:10.1111/trf.13361
Expert comments for publication:
Report provides statistical association between platelet transfusion only. No attempt to demonstrate causation provided.