Delayed hemolytic transfusion reaction associated with Rh antibody anti-f: first reported case.

TitleDelayed hemolytic transfusion reaction associated with Rh antibody anti-f: first reported case.
Publication TypeJournal Article
Year of Publication1985
AuthorsO'Reilly RA, Lombard CM, Azzi RL
JournalVox sanguinis//Vox Sang
Volume49
Issue5
Pagination336 - 9
Date Published1985
ISBN Number0042-9007
Other Numbersxli, 0413606
Keywords*Blood Transfusion/ae [Adverse Effects], *Hemolysis, *Isoantibodies/im [Immunology], Adult, Antibodies/an [Analysis], Erythrocyte Transfusion, Hemoglobins/an [Analysis], Humans, Male, Splenectomy
Abstract

A delayed hemolytic transfusion reaction (DHTR) occurring in a 30-year-old Caucasian man is described. His blood groups were B, CDe/cDE (R1R2, f-) K-, S-s+, Fy (a + b-), and Jk (a + b +). Eight days after receiving two units of packed red blood cells, his urine was strongly positive for hemoglobin; serum-free hemoglobin was 125 mg/dl. Serum contained a clearly reactive Rh antibody of anti-f specificity and a weakly reactive anti-Kell. The DHTR was probably caused by an anti-f alloantibody appearing as an anamnestic response to transfusion of seemingly compatible, but f-positive blood.

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