ESHRE Task Force on Ethics and Law 21: genetic screening of gamete donors: ethical issues.

TitleESHRE Task Force on Ethics and Law 21: genetic screening of gamete donors: ethical issues.
Publication TypeJournal Article
Year of Publication2014
AuthorsDondorp W, De Wert G, Pennings G, Shenfield F, Devroey P, Tarlatzis B, Barri P, Diedrich K, Eichenlaub-Ritter U, Tuttelmann F, Provoost V
JournalHuman reproduction (Oxford, England)//Hum Reprod
Volume29
Issue7
Pagination1353 - 9
Date Published2014
ISBN Number1460-2350
Other Numbershrp, 8701199
Keywords*Oocyte Donation/es [Ethics], *Oocyte Donation/lj [Legislation & Jurisprudence], *Tissue Donors/es [Ethics], *Tissue Donors/lj [Legislation & Jurisprudence], Advisory Committees, Ethics, Medical, Europe, Female, Genetic Testing, Guidelines as Topic, Heterozygote, Humans, Informed Consent, Insemination, Artificial, Heterologous/es [Ethics], Insemination, Artificial, Heterologous/lj [Legislation & Jurisprudence], Male, Patient Safety, risk, United States
Abstract

This Task Force document explores the ethical issues involved in the debate about the scope of genetic screening of gamete donors. Calls for expanded donor screening arise against the background of both occasional findings of serious but rare genetic conditions in donors or donor offspring that were not detected through present screening procedures and the advent of new genomic technologies promising affordable testing of donors for a wide range of conditions. Ethical principles require that all stakeholders' interests are taken into account, including those of candidate donors. The message of the profession should be that avoiding all risks is impossible and that testing should remain proportional.

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