Morbidity and mortality of live lung donation: results from the RELIVE study.

TitleMorbidity and mortality of live lung donation: results from the RELIVE study.
Publication TypeJournal Article
Year of Publication2014
AuthorsYusen RD, Hong BA, Messersmith EE, Gillespie BW, Lopez BM, Brown KL, Odim J, Merion RM, Barr ML, Group RE
JournalAmerican journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons//Am J Transplant
Volume14
Issue8
Pagination1846 - 52
Date Published2014
ISBN Number1600-6143
Other Numbers100968638
Keywords*Living Donors/sn [Statistics & Numerical Data], *Lung Diseases/mo [Mortality], *Lung Diseases/su [Surgery], *Lung Transplantation, Adolescent, Adult, Cohort Studies, Databases, Factual, Female, Humans, Length of Stay, Lung/su [Surgery], Male, Middle Aged, Quality Control, Research Design, Retrospective Studies, Treatment Outcome, Young Adult
Abstract

The Renal and Lung Living Donors Evaluation Study assesses outcomes of live lung (lobectomy) donors. This is a retrospective cohort study at University of Southern California (USC) and Washington University (WASHU) Medical Centers (1993-2006), using medical records to assess morbidity and national databases to ascertain postdonation survival and lung transplantation. Serious complications were defined as those that required significant treatment, were potentially life-threatening or led to prolonged hospitalization. The 369 live lung donors (287 USC, 82 WASHU) were predominantly white, non-Hispanic and male; 72% had a biological relationship to the recipient, and 30% were recipient parents. Serious complications occurred in 18% of donors; 2.2% underwent reoperation and 6.5% had an early rehospitalization. The two centers had significantly different incidences of serious complications (p

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