Transfusion-associated circulatory overload (TACO) and potential risk factors among the inpatient US elderly as recorded in Medicare administrative databases during 2011.

TitleTransfusion-associated circulatory overload (TACO) and potential risk factors among the inpatient US elderly as recorded in Medicare administrative databases during 2011.
Publication TypeJournal Article
Year of Publication2014
AuthorsMenis M., Anderson S., Forshee R., McKean S., Johnson C., Holness L., Warnock R., Gondalia R., Worrall C., Kelman J., Ball R., Izurieta H.
Journal//Vox Sang
Volume106
Issue2
Pagination144 - 152
Date Published2014
ISBN Number0042-9007
Other Numbersxli, 0413606
Keywordsinpatient elderly, Medicare administrative databases, Risk Factors, Transfusion-Associated Circulatory Overload
Abstract

Background and Objectives: Transfusion-associated circulatory overload (TACO) is a serious transfusion complication resulting in respiratory distress. The study's objective was to assess TACO occurrence and potential risk factors among elderly Medicare beneficiaries (ages 65 and older) in the inpatient setting during 2011., Materials and Methods: This retrospective claims-based study utilized Medicare administrative databases in coordination with Centers for Medicare & Medicaid Services. Transfusions were identified by recorded procedure and revenue centre codes, while TACO was ascertained via ICD-9-CM diagnosis code. We evaluated TACO diagnosis code rates overall and by age, gender, race, number of units and blood components transfused. Multivariate logistic regression analyses were used to estimate odds ratios (ORs) and 95% confidence intervals (CIs)., Results: Among 2 147 038 inpatient transfusion stays for elderly in 2011, 1340 had TACO diagnosis code, overall rate of 62[middle dot]4 per 100 000 stays. TACO rates increased significantly with age and units transfused (P

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