TRALI (Transfusion Related Acute Lung Injury)

Status: 
Ready to upload
Record number: 
1486
Adverse Occurrence type: 
MPHO Type: 
Estimated frequency: 
TRALI rates stated prior to and post- implementation of plateletpheresis and plasma from males or nulligravida or HLA-antibody negative parous females. RBC's: 0.5 per 100,000 units; Plateletpheresis:  2.8 to 1.0 per 100,000; Plasma:  3.6 to 0.4 per 1000,000.
Time to detection: 
<6 hours
Alerting signals, symptoms, evidence of occurrence: 
Reports to a large regional blood center with rates reported as TRALI cases per product distributed/tranfused.
Demonstration of imputability or root cause: 
Criteria not presented
Imputability grade: 
1 Possible
Groups audience: 
Reference attachment: 
Suggest references: 
Shaz BH. Bye-bye TRALI: by understanding and innovation. Blood. 2014;123:3374-6.
Expert comments for publication: 
TRALI rates provided in an Editorial addressing TRALI mitigation devices/mediators.