Status:
Ready to upload
Record number:
1408
Adverse Occurrence type:
MPHO Type:
Time to detection:
4 - 5 months
Alerting signals, symptoms, evidence of occurrence:
Elevated liver enzymes; diagnosis of hepatitis C infection delayed by negative serology but made when NAT was positive.
Demonstration of imputability or root cause:
Donor positive by NAT; strains in the donor, two kidney recipients, and tissue recipient were 99.7-100% similar by genetic sequencing; a liver recipient had been previously infected and had different sequences.
Imputability grade:
3 Definite/Certain/Proven
Groups audience:
References:
Reference attachment:
Suggest references:
(CDC), (2011). "Transmission of hepatitis C virus through transplanted organs and tissue - Kentucky and Massachusetts, 2011." MMWR Morb Mortal Wkly Rep 60(50): 1697 - 1700.