Status:
Ready to upload
Record number:
1388
Adverse Occurrence type:
MPHO Type:
Estimated frequency:
This is the only transfusion case ever reported in the literature
Time to detection:
23 days
Alerting signals, symptoms, evidence of occurrence:
A blood donor had an acute onset, febrile illness 4 days after removing an attached tick and 18 hours after donating blood. Colorado tick fever virus was identified in plasma from residual blood in the collections tube, the unit had been stored for 2 weeks. The blood had been transfused to an 82-year-old male patient during exploratory laparotomy for a bowel obstruction due to carcinoma of the colon. Prolonged febrile illness followed and Colorado tick fever virus was isolated from the patient 23 days post transfusion. The patient returned home approximately one month posttransfusion.
Demonstration of imputability or root cause:
Virus found in serum from tubing from donation after 2 weeks' storage, virus isolated from patient 23 days after receipt of transfusion.
Imputability grade:
3 Definite/Certain/Proven
Groups audience:
Suggest new keywords:
CTFV transfusio- transmission
Suggest references:
Leiby DA, Gill JE. Transfusion-transmitted tick-borne infections: a cornucopia of threats. Transfus Med Rev. 2004 Oct;18(4):293-306.
Note:
New voice in the adv. occurrence taxonomy:
Harm to a recipient/Infection/Viral/Colorado tick fever virus