Schistosoma mansoni

Status:

Ready to upload

Record number:

1464

Adverse Occurrence type:

Donor disease without transmission

MPHO Type:

Liver

Estimated frequency:

Up to 10 liver transplants were previously performed with donors infected with schistosoma eggs without disease transmission.

Time to detection:

N/A

Alerting signals, symptoms, evidence of occurrence:

Epithelioid granulomas with necrotic Schistosoma eggs found in the liver biopsy of a living donor who was not treated before donation. Recipient died of sepsis unrelated to schistosomiasis on day +14.

Demonstration of imputability or root cause:

Schistosoma eggs found in liver granulomata without apparent disease transmission to recipient. After the acute phase, S. mansoni remains in the intestine; in the liver, necrotic eggs lead to granulomatous inflammation. Therefore, transmission of Schistosoma via the liver graft is unlikely to occur .

Groups audience:

Infections -- Parasitic

Keywords: