Status:
Ready to upload
Record number:
1262
Adverse Occurrence type:
MPHO Type:
Estimated frequency:
Case Report
Time to detection:
minutes
Alerting signals, symptoms, evidence of occurrence:
Patient received one unit of red blood cells (RBCs), and ten days later was readmitted in painful crisis with Hb of 4.2 g per dL. Patient was given phenotypically matched group O RBCs immediately, but developed hemolytic transfusion reaction (HTR) symptoms of chills, fever, tachycardia, and laboratory signs of hemoglobinemia, hemoglobinuria, and negative DATs.
Demonstration of imputability or root cause:
Cold reactive autoantibody transfusion with blood warmer resulted in no adverse event.
Imputability grade:
3 Definite/Certain/Proven
Groups audience:
Keywords:
References:
Suggest new keywords:
anti-IH, acute hemolytic transfusion reaction (AHTR),
Suggest references:
Campbell, S.A., Shirey, R.S., King, K.E. and Ness, P.M. (2000). An acute hemolytic transfusion reaction due to anti-IH in a patient with sickle cell disease. Transfusion 40(7)828-831.