Strongyloides stercoralis

Risk mostly related to chronic intestinal Strongyloides infection. Rare transmission through transplant, reported in kidney, pancreas, intestine. Classical clinical picture: hyperinfection syndrome with worsening of pulmonary function, starting with wheezing and eventually progression to an ARDS–like picture, with respiratory failure and death. Many patients have concurrent gastrointestinal symptoms, including abdominal pain, dyspepsia, diarrhea or constipation, or severe manifestations including ileus, obstruction and GI bleeding. Classical complication: gram-negative enteric bacteria sepsis, caused by larvae migrating from the bowel through the venous system (-> meningitis, cholecystitis, liver abscess, pancreatitis). Time of Onset: up to 9 months. Eosinophilia not always present. High mortality rate!