Record number:
207
Adverse Occurrence type:
MPHO Type:
Estimated frequency:
Most recent risk assessment for leukemia, lymphoma and plasmacytoma (Council of Europe, 2022):
Leukaemia, lymphoma and plasmacytoma diagnosed during donor procurement: These cancers are classified as an unacceptable risk for organ donation. Leukaemia, lymphoma and plasmacytoma in the donor history: Active (acute or chronic) leukaemia, lymphoma and plasmacytoma are an unacceptable risk for organ donation. Treated acute leukaemia and lymphoma after a definite disease-free interval of 10 years may be considered for organ donation with an assumed high risk for transmission.
Time to detection:
5 years
Alerting signals, symptoms, evidence of occurrence:
Eczematous plaques and nodules on the lower part of both legs, similar to donor who died 1 month prior of lymphoma. Atypical T cells infiltrating the dermis and subcutis. In retrospect, lesion had been there for 1 year.
Demonstration of imputability or root cause:
Histologic examination of a nodule revealed many similarities to the subcutaneous panniculitic T-cell lymphoma identified in the donor. Microsatellite PCR identity between donor and recipient tumors. TCRgamma sequence identity.
Imputability grade:
3 Definite/Certain/Proven
Groups audience:
Keywords:
Suggest new keywords:
Living donor
Case report
Suggest references:
aaa