Epstein-Barr virus lymphoproliferative disease of donor origin after kidney transplantation: a case report

TitleEpstein-Barr virus lymphoproliferative disease of donor origin after kidney transplantation: a case report
Publication TypeJournal Article
Year of Publication1995
AuthorsRenoult E, Aymard B, Gregoire MJ, Bellou A, Hubert J, Hestin D, Audouin J, Lederlin P, Kessler M
JournalAm J Kidney Dis
Volume26
Issue1
Pagination84 - 7
Date PublishedJul
ISSN0272-6386 (Print) 0272-6386 (Linking)
Accession Number7611274
Keywords*Herpesvirus 4, Human / genetics, *Tissue Donors, Aged, B-Lymphocytes, Chromosome Inversion, Chromosomes, Human, Pair 1, DNA Transposable Elements / genetics, DNA, Viral / genetics, Female, Herpesviridae Infections / genetics / *transmission / virology, Humans, Kidney Transplantation / *adverse effects, Lymphoproliferative Disorders / *etiology / genetics / virology, Transforming Growth Factor beta / genetics, Tumor Virus Infections / genetics / *transmission / virology
Abstract

A case of an Epstein-Barr virus (EBV)-associated B lymphoproliferative disorder presented as a renal transplant obstruction is reported. The diagnosis was made from histology, immunohistochemistry, and EBV expression studies. Cytogenetic analysis showed the tumor to be of donor origin and revealed chromosomal translocation 46, XY, inv (1)(p35; q41), involving the EBV insertion site 1(1p35) and transforming growth factor beta 2(1q41) loci.

DOI
Notify Library Reference ID1311

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