Postrenal transplant non-EBV multiple myeloma of donor origin

TitlePostrenal transplant non-EBV multiple myeloma of donor origin
Publication TypeJournal Article
Year of Publication2006
AuthorsPeri N, Kussick S, Bakthavatsalam R, Mitsumori L, Dighe M
JournalAm J Transplant
Volume6
Issue2
Pagination419 - 22
Date PublishedFeb
Accession Number16426330
KeywordsAged, Bone Marrow / pathology, Chromosomes, Human, Y, Female, Herpesvirus 4, Human / isolation & purification, Humans, In Situ Hybridization, Fluorescence, Kidney Failure, Chronic / *surgery, Kidney Transplantation / *adverse effects / pathology, Multiple Myeloma / *etiology / genetics / pathology, Postoperative Complications / *diagnosis / pathology, Tissue Donors
Abstract

Multiple myeloma occurring after solid organ transplantation is a rare condition, with only a few case reports found in the literature. We report a case of Epstein-Barr virus-negative, posttransplant multiple myeloma in a 67-year-old female, presenting 18 months after renal transplantation. Interestingly, fluorescence in situ hybridization analysis of the tumor revealed a Y chromosome in the majority of the cells, indicating that the neoplasm was derived from the donor kidney. To our knowledge, this represents the first reported case with these features.
Notify Library Reference ID1264

Related Incidents