IgA myeloma of donor origin arising 7 years after allogeneic renal transplant

TitleIgA myeloma of donor origin arising 7 years after allogeneic renal transplant
Publication TypeJournal Article
Year of Publication2000
AuthorsGrey M, Townsend N, Lappin D, Roberts I, Stanford R, Sheldon M, Tate D, Short C, Lucas G
JournalBr J Haematol
Volume108
Issue3
Pagination592 - 4
Date PublishedMar
ISSN0007-1048 (Print) 0007-1048 (Linking)
Accession Number10759718
Keywords*Immunoglobulin A, Adult, DNA Fingerprinting, Fatal Outcome, Humans, Kidney Transplantation / *adverse effects, Male, Multiple Myeloma / *etiology / genetics / immunology, Time Factors, Transplantation, Homologous
Abstract

We report the case of a 38-year-old man who developed IgA myeloma of donor origin 7 years after allogeneic renal transplant. The diagnosis of multiple myeloma was unequivocal and based on positive results from serum electrophoresis, skeletal survey and bone marrow investigations. The donor origin of the myeloma cells was confirmed by DNA fingerprinting. We believe this is the first reported case of disseminated multiple myeloma of donor origin developing after allogeneic renal transplant and, as such, gives some insight into the natural history and biology of the disease.
DOI
Notify Library Reference ID608

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