Title | A fatal case of West Nile virus infection in a bone marrow transplant recipient |
Publication Type | Journal Article |
Year of Publication | 2003 |
Authors | Hiatt B, DesJardin L, Carter T, Gingrich R, Thompson C, de Magalhaes-Silverman M |
Volume | 37 |
Issue | 9 |
Pagination | 29 |
Date Published | Nov |
Abstract | West Nile virus (WNV) can cause severe, potentially fatal neurological illnesses, which include encephalitis, meningitis, Guillain-Barré syndrome, and anterior myelitis. Because of the short viremic phase, WNV infection is most commonly diagnosed by detection of immunoglobulin M antibody to WNV in serum or cerebrospinal fluid (CSF). We describe a patient with T cell lymphoma who had undergone a T cell-depleted bone marrow transplantation and developed fatal WNV infection. The results of serological tests of blood samples and of CSF tests were negative. Diagnosis was made postmortem by a positive result of reverse-transcriptase polymerase chain reaction (ABI 7700; TaqMan) for WNV in stored CSF and serum samples. |
DOI | 10.1086/378891 |
Alternate Journal | Clin Infect Dis. |
Notify Library Reference ID | 4780 |