Adverse Occurrence type:
Time to detection:
Alerting signals, symptoms, evidence of occurrence:
Anemia, thrombocytopenia, arthralgias, erythema infectiosum
Demonstration of imputability or root cause:
The BM donor was a 19-year-old asymptomatic brother who had parvovirus B19 viraemia at the time of bone marrow harvest. Sequencing VP2gene donor and recipient showed a perfect match of DNA sequences, confirming the mode of transmission.
Parvovirus B19 transmitted by bone marrow