Adverse Occurrence type:
Time to detection:
Alerting signals, symptoms, evidence of occurrence:
Rapidly growing mass in right mandible. Biopsy reveals a malignant small round blue cell tumor with the immunohitochemistry profile of a Primary Neuroectodermic Tumor (PNET). Staging evaluation reveales the tumor in the right mandible with bone marrow involvement.
Demonstration of imputability or root cause:
Condition present in the donor (autopsy results available seven weeks after transplantation, which found a pineoblastoma with meningeal spread. Recipient's tumor and donor's pineoblastoma share the same immunophenotype and HLA type.