Sickle crisis

Record number: 
880
Adverse Occurrence type: 
GCSF-related
MPHO Type: 
Apheresis
Estimated frequency: 
Rare
Alerting signals, symptoms, evidence of occurrence: 
Pain during days of injections
Demonstration of imputability or root cause: 
Definite/probable. Temporal relationship.
Keywords: 
G-CSF (granulocyte colony-stimulating factor)
injections
toxicity
pain
PBSC (peripheral blood stem cells)
apheresis
donor reaction
death
allogeneic
allogeneic related
References: 
Fatal sickle cell crisis after granulocyte colony-stimulating factor administration
Granulocyte colony-stimulating factor-induced sickle cell crisis and multiorgan dysfunction in a patient with compound heterozygous sickle cell/B+ thalassemia
Suggest references: 
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