Human Immunodeficiency Virus (HIV)

Record number: 
Adverse Occurrence type: 
MPHO Type: 
Alerting signals, symptoms, evidence of occurrence: 
12 recipients had bone allografts from a HIV-infected donor, 4 became HIV-positive. The donor was not been tested before the grafts were harvested, as HIV-antibody detection was not possible at the time (October 1984); no HIV-antibody kits had yet been developed. Subsequent testing of the archived serum for HIV antibodies gave a positive result.
Demonstration of imputability or root cause: 
Proven by archive serum testing.
Imputability grade: 
3 Definite/Certain/Proven
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