Hepatitis B Virus (HBV) transmission

Record number: 
554
Adverse Occurrence type: 
MPHO Type: 
Alerting signals, symptoms, evidence of occurrence: 
Retrospective study
Demonstration of imputability or root cause: 
Eight male HBV carriers whose wives were negative for any HBV marker and their eight aborted fetuses who had been infected with HBV in utero, were studied. HBV DNA was detected in the semen and spermatid of male HBV carriers. The homologies of HBV sequences between father and fetus were very high. Six father/fetus pairs had the same subtype. finding suggested that HBV vertical transmission from father to fetus was present.
Imputability grade: 
3 Definite/Certain/Proven
Suggest references: 
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