Record number:
464
Adverse Occurrence type:
MPHO Type:
Estimated frequency:
Two large series of 4,312 and 662 BMT patients, showed incidences of 0.28% and 0.45% but most published cases are of reactivation, as recipient seropositive pre-transplantation
Time to detection:
7 days - 6 weeks
Alerting signals, symptoms, evidence of occurrence:
fever, cardiomyopathy, encephalitis, respiratory failure
Demonstration of imputability or root cause:
Possible in some cases, as recipient seronegative pre-transplant but donor serostatus not always available; majority of cases reported are not due to graft-related infection (cases of non primary toxoplasmosis)
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