Adverse Occurrence type:
Time to detection:
Alerting signals, symptoms, evidence of occurrence:
Lethargy, ataxia, nausea developed 18 months after second corneal transplantation. Deteriorated rapidly and died 8 months after onset. Autopsy confirmed CJD. Donor was 55 year old male who died of CJD confirmed at autopsy.
Demonstration of imputability or root cause:
Level 4. Certain. CJD was confirmed at autopsy in both the donor and the cornea recipient