Adverse Occurrence type:
Time to detection:
Alerting signals, symptoms, evidence of occurrence:
Fever, altered mental status associated with a pancytopenia, hepatosplenomegaly, and neurologic signs.
Demonstration of imputability or root cause:
Blood smear; marrow aspiration showed P. falciparum parasites and proliferation of mature histiocytes with hemophagocytosis. First reported case by malaria after BMT.
Plasmodium falciparum causing hemophagocytic syndrome after allogeneic blood stem cell transplantation