Clonorchis sp.

Record number: 
Adverse Occurrence type: 
MPHO Type: 
Alerting signals, symptoms, evidence of occurrence: 
6 cases described. In 4 cases, donor shows abnormalities in bile ducts and ova of Chlonorchis sp. were detected in stool samples. Case 2: normal preoperative CT scan, but perioperative documentation of minimal bile duct inflammation. In all cases identification of the parassite in bile ducts and intraoperative irrigation of bile duct was performed. 3 patients received treatement with praziquantel: 2 cases provided to the donor (Case 2/3), 1 case donor and recipient (Case 4). In 2 cases, no therapy was provided(case 5+6). 1 Patient developed early postop. blockage of the hepaticojejunostomy slint (Case 5). Parassites was not identified further and no abnormalities in liver function was observed in the 2 patients. No case of dissemination described. Parassite causes primarly major mechanical obstruction problems in bile ducts. Macroscopic elimination of parassites + irrigation should be performed. Cases 7-21. Case series 2010. All recipient has confirmed transmission (donor + serological and presence of ova; recipient negative). All recipients receives praziquantel after Tx. No case of dissemination. Liver function improved rapidly after the operation in all of the patients. Postoperative biliary complications occurred in 2 patients. No ova were detected in the bile or feces of any of the patients postoperatively. This report suggest that livers infested with C. sinensis can be used as donor organs for liver transplantation.
Demonstration of imputability or root cause: 
Proven disease (macroscopic demonstration of parassite + ova in donor)
Imputability grade: 
3 Definite/Certain/Proven
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