Record number:
386
Adverse Occurrence type:
MPHO Type:
Estimated frequency:
3 of 3 recipients (100%) developed Chagas disease
Alerting signals, symptoms, evidence of occurrence:
Uncertain; liver recipient was traced back and identified after febrile kidney-pancreas recipient was found infected by T cruzi. The liver recipient, a 32 year old female, received several weeks of Nifurtimox therapy, but died of sepsis and multiorgan failure four months after transplant, cause of death thought to be unrelated to T cruzi.
Demonstration of imputability or root cause:
Likely transmission. Although donor not tested, the donor was an immigrant from Central America. All three recipients of organs developed Chagas disease. All 3 recipient were peripheral smear and blood culture positive for T. cruzi
Imputability grade:
2 Probable
Keywords:
Suggest references:
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