Glomerulopathy secondary to ABO mismatch

Record number: 
Adverse Occurrence type: 
MPHO Type: 
Time to detection: 
155 days
Alerting signals, symptoms, evidence of occurrence: 
A mild acute transplant glomerulitis, noted at the 155th day post-transplantation, progressed to pronounced chronic transplant glomerulopathy over 5 yr. In the specimen of the last biopsy, at 5 yr post-transplantation, glomeruli demonstrated an exudative hyaline lesion, which was characteristic of diabetic nephropathy in addition to chronic transplant glomerulopathy.
Demonstration of imputability or root cause: 
Patient recovered from delayed hyperacute rejection (DHAR) immediately post-transplantation, her graft function deteriorated gradually. Possibly related to combination of diabetes and ABO chronic rejection.
Imputability grade: 
1 Possible
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