Registry series: Medulloblastoma (2001)

Most recent risk assessment for medulloblastoma (Council of Europe, 2022): Childhood medulloblastomas are the CNS primitive tumours that metastasize most frequently outside the CNS. The risk may be increased if prior ventriculo-peritoneal or ventricular-atrial shunts, tumour resection or cranial chemo-/radiotherapy have been performed. Organs from potential donors with medulloblastomas (WHO grade IV) are considered intermediate to high risk for tumour transmission, depending on different international recommendations, which will be adjusted with increasing evidence. They should be used exclusively for transplants where the recipient’s risk of dying while on the waiting list is greater than the risk of tumour transmission.