Record number:
257
Adverse Occurrence type:
MPHO Type:
Time to detection:
12 weeks
Alerting signals, symptoms, evidence of occurrence:
Wasting syndrome, liver failure (possibly related to GVHD); leukocytosis with immunoblasts and plasmacytoid lymphocytes; lymphadenopathy; hepatosplenomegaly; immunoblastic sarcoma (lymphoma) noted;
Demonstration of imputability or root cause:
Post mortem: Diffuse infiltratiive immunoblastic sarcoma (lymphoma); extensive GI track involvement; liver, lungs and kidneys also involved. Both large and small lymphoblastoid cells present with high mitotic activity.
Suggest references:
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