Case report: Acute myeloid leukemia (AML) (2009)

Record number:

239

Adverse Occurrence type:

Leukemia, myeloid, acute myelogenous (includes myeloid sarcoma)

MPHO Type:

Estimated frequency:

- Most recent risk assessment for leukemia, lymphoma and plasmacytoma (Council of Europe, 2025): Leukaemia, lymphoma and plasmacytoma diagnosed during donor procurement: These cancers are classified as an unacceptable risk for organ donation. Leukaemia, lymphoma and plasmacytoma in the donor history: Active (acute or chronic) leukaemia, lymphoma and plasmacytoma are an unacceptable risk for organ donation. Treated acute leukaemia and lymphoma after a definite disease-free interval of 10 years may be considered for organ donation with an assumed high risk for transmission.

Time to detection:

18 months

Alerting signals, symptoms, evidence of occurrence:

Both donor and recipient (brother and sister, respectively) developed synchronous AML

Demonstration of imputability or root cause:

Both kariotypes were identical.

Imputability grade:

3 Definite/Certain/Proven

Groups audience:

Malignancy

Keywords:

cytogenetics