Chronic pain following laparoscopic living-donor nephrectomy

Status: 
Ready to upload
Record number: 
2130
Adverse Occurrence type: 
MPHO Type: 
Estimated frequency: 
In the study group of 512 living laparoscopic kidney donors, 29 (5.7%) reported the presence of chronic pain related to their donor nephrectomy. The highest prevalence (12.2%) was reported in the group with a follow‐up time of 3 to 24 months after surgery. Percentages of donors reporting chronic pain at different time intervals following surgery were -- 2-4 years=5.2%; 4-6 years=2.2%; 6-8 years=6.6%; 8-10 years=4.8%; >10 years=4.3%.
Time to detection: 
The highest percentage of donors reporting chronic pain was in the group that was surveyed 3-24 months following donation (12.2%). Lower percentages of donors (2.2%-6.6%) reported pain across the 2-10 years following donation.
Alerting signals, symptoms, evidence of occurrence: 
The primary analysis consisted of the prevalence of chronic pain following laparoscopic kidney donation. All included donors were asked if they still experienced pain related to their donor nephrectomy at the time that they were approached for this study (0-10 years following donation). Patients were considered to have chronic pain if their answer was “yes.”
Demonstration of imputability or root cause: 
Donors self-reported chronic pain associated with the donation.
Imputability grade: 
2 Probable
Groups audience: 
Suggest new keywords: 
laparoscopic kidney donation, chronic pain, HRQoL
Reference attachment: 
Suggest references: 
1) Chronic pain following laparoscopic living-donor nephrectomy: Prevalence and impact on quality of life. Am J Transplant. 2019 Oct;19(10):2825-2832 2) "Re: Chronic Pain following Laparoscopic Living-Donor Nephrectomy: Prevalence and Impact on Quality of Life." The Journal of Urology, 203(4), p. 652 (NO ACCESS)
Expert comments for publication: 
In addition to assessing the prevalence of chronic pain following laparoscopic kidney donation, the study also examined predictors of chronic pain. In multivariate analyses, the presence of severe early postoperative pain, previous abdominal surgery, and preexisting pain problems predicted the development of chronic pain following laparoscopic kidney donation. Overall HRQoL -- assessed with the RAND SF-36 -- of donors with chronic pain was significantly lower than those without chronic pain.