Status:
Ready to upload
Record number:
2074
Adverse Occurrence type:
MPHO Type:
Estimated frequency:
Renal angiomyolipoma is typically a benign tumor and incidental finding estimated to occur with a frequency between 0.02-0.2%. Frequency is higher in conditions of tuberous sclerosis or lymphangioleiomyomatosis (https://www.kidney-international.org/article/S0085-2538(15)50139-7/fulltext). The Council of Europe does not discuss this lesion. It may rarely coexist with other renal cell neoplasms.
Time to detection:
3 months; found during biopsy to assess rejection
Alerting signals, symptoms, evidence of occurrence:
Rejection- no symptoms referable to angiomyolipoma
Demonstration of imputability or root cause:
Biopsy diagnosis of allograft kidney; tuberous sclerosis and angiomyolipoma also found at donor autopsy.
Imputability grade:
3 Definite/Certain/Proven
Groups audience:
References:
Suggest new keywords:
Malignancy
Case report
Deceased donor
Kidney transplant
Angiomyolipoma
Suggest references:
1. Marsidi P. Re: successful living related kidney transplantation despite renal angiomyolipoma in situ. The Journal of urology. 2000;163(3):924.
2. Marsidi PJ and Wise HA, II. Tuberous sclerosis and angiomyomolipomatous kidney conditions. Ohio State Med J 79: 449, 1983. https://archive.org/details/ohiostatemedical7911ohio/page/448/mode/2up
Note:
The pdf is a letter in response to the original article; The original article can be found in the link at the end of reference #2 in "suggested references". You will have to scroll to page 449; I could not find a pdf version of this. Mike N.
Expert comments for publication:
Allograft nephrectomy was performed at nine months (documented in followup letter to the editor listed above) due to rejection. No apparent symptoms related to angiomyolipoma, although the original author raised the possibility of the tumor facilitating rejection. We consider this unlikely.