Status:
Ready to upload
Record number:
2020
Adverse Occurrence type:
MPHO Type:
Estimated frequency:
Arterial puncture: 0.014%; Hematoma: 0.32-1.05%; Nerve injury: 0.016 - 0.032%; Pseudoaneurysm: 0.1% - 0.4% of arterial punctures; AV Fistula: extremely rare with 4 reported cases; Compartment syndrome: very rare with 2 documented cases; Upper-extremety DVT: very rare, 2 reported cases; Nerve injury: 0.9%; Chronic regional pain syndrome: very rare; Local allergic reactions: 0.001%; Infection and thrombophlebitis: uncommon, incidence unknown.
Time to detection:
Arterial puncture: immediate; Hematoma: 1-3 days; Nerve injury: immediate; Pseudoaneurysm and AV Fistula: 2-3 weeks; Compartment syndrome: within 12 hours; Thrombophlebitis: within 48 hours
Alerting signals, symptoms, evidence of occurrence:
Contusions and hematomas: flat or raised lesions with skin discoloration, depending on the age of the lesion.
Arterial puncture: bright red blood, rapid filling of the collection bag, pulsing tubing; high incidence of hematomas.
Pseudoaneurysm: bruits, pulsatile mass; generally require vascular surgery for evacuation of hematomas and repair of arterial sites.
AV Fistula: pulsating, elongated mass, usually with a thrill or bruit; vascular surgery is required for remove AV fistula and reestablish normal blood flow.
Compartment syndrome: swelling of arm, pulselessness, pallor, pain in arm; surgical decompression and fasciotomy as early as possible to prevent loss of function and necrosis.
Upper-extremity DVT: pain, antecubital tenderness, arm swelling.
Nerve injury: intense shooting pain immediately upon needle insertion, distal paresthesias in 82%
Thrombophlebitis: red line extending up the arm from the venipuncture site; arm infection: usually cellulitis.
Demonstration of imputability or root cause:
Demonstration of the appropriate signs and symptoms within the appropriate time frame from donation
Groups audience:
Keywords:
References:
Suggest new keywords:
donor complications, needle injuries, hematoma, AV Fistula, pseudoaneurysm, compartment syndrome, chronic regional pain syndrome, thrombophlebitis, allergic reaction
Reference attachment:
Suggest references:
Arm Complications After Manual Whole Blood Donation. Newman B. Transfus Med Rev. 2013 Jan;27(1):44-9.
Estimating the probability of a blood donation adverse event based on 1000 interviewed whole-blood donors. Newman BH, Roth AJ. Transfusion. 2005 Nov; 45(11):1715-21.
Upper-extremity Deep Vein Thrombosis Complicating Apheresis in a Healthy Donor. Haba Y, Oshima H, Naito T, Takasu K, Ishimaru F. Intern Med. 2017; 56(13):1739-1743. Epub 2017 Jul 1.
Upper-extremity deep venous thrombosis after whole blood donation: report of three cases from a single blood center. Newman B, Rajpurkar M, Ozgonenel B, Lal A, Kuriakose P.
Transfusion. 2015 Jun; 55(6):1290-3. Epub 2015 Feb 25.
Note:
There are some other articles I need to append after I find them
Expert comments for publication:
This is an excellent summary of the adverse events that can occur due to the insertion of the needle into an arm for blood collection. The other main category of donor adverse events is due to vasovagal reaction and it is not included in this paper.