Status:
Ready to upload
Record number:
1850
Adverse Occurrence type:
MPHO Type:
Time to detection:
Not reported. The mean hospital stay was 6 days.
Alerting signals, symptoms, evidence of occurrence:
Of the first 5 cases of Living Donor Uterus Transplantation performed in the US, the following adverse occurrences were identified in the donors: 1. dehiscence of the vaginal cuff, a significant postoperative complication, that was surgically repaired; 2. temporary gluteal cramping with mobilization that resolved in three weeks; 3. urinary tract infection that resolved with oral antibiotics; 4. minor depression, possibly due to the hormonal changes related to the simultaneous salpingo-oophorectomy performed for that patient; 5. fecal impaction requiring digital disimpaction.
Demonstration of imputability or root cause:
Postoperative complication (direct result of the operation)
Imputability grade:
3 Definite/Certain/Proven
Groups audience:
Reference attachment:
Suggest references:
G. Testa, E. C. Koon, L. Johannesson, et al. Living Donor Uterus Transplantation: A Single Center’s Observations and Lessons Learned from Early Setbacks to Technical Success. Am J Transplant. 2017 Apr 22
Note:
TO ADD: Organs-> Composite tissues grafts -> Uterus - ok
Expert comments for publication:
The first 5 cases of Living Donor Uterus Transplantation performed in the US and the lessons learned are described in this paper. New clinical trials in order to accumulate data to further optimize the procedure in relation to safety and efficiency are needed. In this regard, the creation of a global registry to follow donors, recipients and children born after uterus transplantation is central.